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ITA3144

ITA3144-2
ITA3144-1
ITA3144-2
ITA3144-1
ITA3144
  • Gene/Protein: TRIM14
  • Product Description: Immunotag™ TRIM14 Antibody
280.0000
Price in reward points: 280

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Immunotag™ TRIM14 Antibody
Antibody Specification
Datasheet

Target Protein TRIM14
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC
Recommended Dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen A synthesized peptide derived from human TRIM14.
Specificity TRIM14 antibody detects endogenous levels of TRIM14.
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name TRIM14
Accession No. Q14142
Alternate Names 5830400N10Rik; KIAA0129; pub; TRI14_HUMAN; TRIM14; tripartite motif protein 14; tripartite motif protein TRIM14; tripartite motif-containing 14; Tripartite motif-containing protein 14;
Description Plays a role in the innate immune defense against viruses. Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane and thereby recruiting NF-kappa-B essential modulator IKBKG/NEMO to the MAVS signalosome, leading to the activation of both the IFN regulatory factor 3/IRF3 and NF-kappa-B pathways (PubMed:24379373). Positively regulates the CGAS-induced type I interferon signaling pathway by stabilizing CGAS and inhibiting its autophagic degradation (PubMed:27666593).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 50 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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