ITA5239
ITA5239
- Catalog: ITA5239
- Gene/Protein: MOV10L1
- Product Description: Immunotag™ MOV10L1 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | MOV10L1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | MOV10L1 Antibody detects endogenous levels of total MOV10L1 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | MOV10L1 |
| Accession No. | Q9BXT6 |
| Alternate Names | Cardiac helicase activated by MEF2 protein; Cardiac specific RNA helicase; CHAMP; Csm; M10L1_HUMAN; Moloney leukemia virus 10 like protein 1; Moloney leukemia virus 10-like protein 1; MOV10 like 1; MOV10 like protein 1; MOV10-like protein 1; MOV10L1; Mov10l1, Moloney leukemia virus 10 like 1, homolog (mouse); Putative helicase Mov10l1; |
| Description | ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 140 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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