ITA5334
ITA5334
- Catalog: ITA5334
- Gene/Protein: SEMA7A
- Product Description: Immunotag™ SEMA7A Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | SEMA7A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | SEMA7A Antibody detects endogenous levels of total SEMA7A |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | SEMA7A |
| Accession No. | O75326 |
| Alternate Names | CD 108; CD108; CD108 antigen; CDw108; H Sema K1; H Sema L; H-SEMA-K1; H-Sema-L; JMH; JMH blood group antigen; John Milton Hagen blood group H Sema K1; John Milton Hargen human blood group Ag; John-Milton-Hargen human blood group Ag; MGC126692; MGC126696; SEM7A_HUMAN; Sema domain immunoglobulin domain (Ig) and GPI membrane anchor 7A; Sema K1; Sema L; SEMA7A; SEMAK1; SEMAL; Semaphorin 7A GPI membrane anchor; Semaphorin K1; Semaphorin L; Semaphorin-7A; Semaphorin-K1; Semaphorin-L; Semaphorin7a; |
| Description | Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 75 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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