ITA5846
ITA5846
- Catalog: ITA5846
- Gene/Protein: GPR31
- Product Description: Immunotag™ GPR31 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | GPR31 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500~1:1000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | GPR31 Antibody detects endogenous levels of total GPR31 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | GPR31 |
Accession No. | O00270 |
Alternate Names | 12-(S)-HETE acid receptor; 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (HETE) receptor; 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor; 12-(S)-HYDROXYEICOSATETRAENOIC ACID RECEPTOR; 12-HETER; bA517H2.2 (G protein coupled receptor 31); G protein coupled receptor 31; GPR31; HETER; HETER1; OTTHUMP00000017616; Probable G protein coupled receptor 31; |
Description | High-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 33 KD |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |