ITA7221
ITA7221
- Catalog: ITA7221
- Gene/Protein: MCM4
- Product Description: Immunotag™ MCM4 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | MCM4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC,IF/ICC,ELISA |
Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthetic peptide of human MCM4 |
Specificity | MCM4 Antibody detects endogenous levels of total MCM4 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | MCM4 |
Accession No. | P33991 |
Alternate Names | 19G; AI325074; AU045576; CDC 21; CDC 54; CDC21; CDC21 homolog; CDC21, S. pombe, homolog of; CDC54; Cell division cycle 21, S. pombe, homolog of; DNA replication licensing factor MCM 4; DNA replication licensing factor MCM4; hCdc 21; hCdc21; Homolog of S. pombe cell devision cycle 21; KIAA4003; mcdc21; MCM 4; MCM 4 minichromosome maintenance deficient 4; mcm4; MCM4 minichromosome maintenance deficient 4; MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae); MCM4_HUMAN; Mcmd4; MGC33310; Minichromosome maintenance 4; Minichromosome maintenance complex component 4; Minichromosome maintenance deficient (S. cerevisiae) 4; Minichromosome maintenance deficient 4; Minichromosome maintenance deficient 4 homolog (S. cerevisiae); Minichromosome maintenance, S. cerevisiae, homolog of, 4; mKIAA4003; NKCD; NKGCD; P1 CDC21; P1-CDC21; P1CDC21; |
Description | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 97kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |