ITA7726
ITA7726
- Catalog: ITA7726
- Gene/Protein: ACOD1
- Product Description: Immunotag™ IRG1 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | IRG1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human IRG1 |
| Specificity | IRG1 Antibody detects endogenous levels of total IRG1 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | ACOD1 |
| Accession No. | A6NK06 |
| Alternate Names | ACOD1; Aconitate decarboxylase 1; Aconitate decarboxylase; CAD; Cis aconitate decarboxylase; Immune responsive gene 1 protein homolog; Immune-responsive gene 1 protein homolog; Immunoresponsive 1 homolog (mouse); Irg1; IRG1_HUMAN; OC116; OPTB1; TCTIRC7; |
| Description | Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 55 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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