ITA7895
ITA7895
- Catalog: ITA7895
- Gene/Protein: MESDC2
- Product Description: Immunotag™ MESDC2 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | MESDC2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human MESDC2 |
| Specificity | MESDC2 Antibody detects endogenous levels of total MESDC2 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | MESDC2 |
| Accession No. | Q14696 |
| Alternate Names | BOCA; KIAA0081; LDLR chaperone MESD; MESD; MESD_HUMAN; MESDC 2; mesdc2; Mesoderm development candidate 2; Mesoderm development protein; Renal carcinoma antigen NY REN 61; Renal carcinoma antigen NY-REN-61; |
| Description | Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (By similarity). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 26 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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