ITA8000
ITA8000
- Catalog: ITA8000
- Gene/Protein: RNLS
- Product Description: Immunotag™ RNLS Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | RNLS |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:1000-3000 IHC 1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human RNLS |
| Specificity | RNLS Antibody detects endogenous levels of total RNLS |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | RNLS |
| Accession No. | Q5VYX0 |
| Alternate Names | 6530404N21Rik; AI452315; AW060440; C10orf59; Chromosome 10 open reading frame 59; FLJ11218; HGNC:25641; Hypothetical protein LOC55328; MAO C; MAO-C; mMAO C; Monoamine oxidase C; Monoamine oxidase-C; Renalase; Renalase FAD dependent amine oxidase; RNLS; RNLS_HUMAN; |
| Description | Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 38 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|