ITA8026
ITA8026
- Catalog: ITA8026
- Gene/Protein: CDT1
- Product Description: Immunotag™ CDT1 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CDT1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:1000-3000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human CDT1 |
Specificity | CDT1 Antibody detects endogenous levels of total CDT1 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | CDT1 |
Accession No. | Q9H211 |
Alternate Names | CDT 1; cdt1; CDT1_HUMAN; Chromatin licensing and DNA replication factor 1; DNA replication factor; DNA replication factor Cdt1; Double parked; Double parked Drosophila homolog of; Double parked homolog; DUP; Retroviral integration site 1; Retroviral integration site 2; Retroviral integration site1; Retroviral integration site2; RIS 2; RIS2; |
Description | Required for both DNA replication and mitosis (PubMed:11125146, PubMed:22581055, PubMed:21856198, PubMed:14993212, PubMed:26842564). DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC)(PubMed:14672932). Required also for mitosis by promoting stable kinetochore-microtubule attachments (PubMed:22581055). Potential oncogene (By similarity). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 63 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |