ITA8216
ITA8216
- Catalog: ITA8216
- Gene/Protein: DOCK2
- Product Description: Immunotag™ DOCK2 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | DOCK2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:1000-3000 IF/ICC 1:200-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human DOCK2 |
| Specificity | DOCK2 Antibody detects endogenous levels of total DOCK2 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | DOCK2 |
| Accession No. | Q92608 |
| Alternate Names | Dedicator of cyto kinesis 2; Dedicator of cytokinesis 2; Dedicator of cytokinesis protein 2; DOCK 2; FLJ46592; KIAA0209; |
| Description | Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 212 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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