ITA8411
ITA8411
- Catalog: ITA8411
- Gene/Protein: JTB
- Product Description: Immunotag™ JTB Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | JTB |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:1000-3000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human JTB |
| Specificity | JTB Antibody detects endogenous levels of total JTB |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | JTB |
| Accession No. | O76095 |
| Alternate Names | hJT; HJTB; HSPC222; JTB; JTB_HUMAN; Jumping translocation breakpoint; Jumping translocation breakpoint protein; OTTHUMP00000034759; PAR; PAR protein; Prostate androgen regulated protein; Prostate androgen-regulated protein; Protein JTB; |
| Description | Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 16 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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