ITA9018
ITA9018
- Catalog: ITA9018
- Gene/Protein: BAAT
- Product Description: Immunotag™ BAAT Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | BAAT |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:1000-3000 IHC 1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human BAAT |
| Specificity | BAAT Antibody detects endogenous levels of total BAAT |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | BAAT |
| Accession No. | Q14032 |
| Alternate Names | FLJ20300; BAAT; BAAT_HUMAN; BACAT; BAT; Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid CoA:amino acid N acyltransferase; Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase; Bile acid Coenzyme A: amino acid N acyltransferase; Bile acid-CoA:amino acid N-acyltransferase; Glycine N choloyltransferase; Glycine N-choloyltransferase; Long chain fatty acyl CoA hydrolase; Long-chain fatty-acyl-CoA hydrolase; MGC104432; |
| Description | Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 46 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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