ITA9344
ITA9344
- Catalog: ITA9344
- Gene/Protein: LILRB1
- Product Description: Immunotag™ LILRB1 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | LILRB1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human LILRB1 |
| Specificity | LILRB1 Antibody detects endogenous levels of total LILRB1 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | LILRB1 |
| Accession No. | Q8NHL6 |
| Alternate Names | CD85; CD85 antigen; CD85 antigen like family member J; CD85 antigen-like family member J; CD85j; CD85j antigen; Ig like transcript 2; ILT 2; ILT-2; ILT2; immunoglobulin like transcript 2; Immunoglobulin-like transcript 2; leukocyte Ig like receptor 1; Leukocyte immunoglobulin like receptor 1; leukocyte immunoglobulin like receptor subfamily B member 1; Leukocyte immunoglobulin like receptor subfamily B member 1 precursor; leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform; leukocyte immunoglobulin like receptor, subfamily B, member 1; Leukocyte immunoglobulin-like receptor 1; Leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LILRB1; LIR 1; LIR-1; LIR1; LIRB1_HUMAN; MIR 7; MIR-7; MIR7; Monocyte/macrophage immunoglobulin like receptor 7; Monocyte/macrophage immunoglobulin-like receptor 7; PIR B; PIRB; |
| Description | Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 71 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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