ITA9467
ITA9467
- Catalog: ITA9467
- Gene/Protein: OAZ3
- Product Description: Immunotag™ OAZ3 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | OAZ3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human OAZ3 |
| Specificity | OAZ3 Antibody detects endogenous levels of total OAZ3 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | OAZ3 |
| Accession No. | Q9UMX2 |
| Alternate Names | Antizyme 3; AZ3; OAZ t; OAZ3; OAZ3_HUMAN; ODC-Az 3; Ornithine decarboxylase antizyme 3; RP11-98D18.13-004; Testicular secretory protein Li 31; TISP15; |
| Description | Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells (By similarity). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 27 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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