ITA9728
ITA9728
- Catalog: ITA9728
- Gene/Protein: USP34
- Product Description: Immunotag™ USP34 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | USP34 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human USP34 |
| Specificity | USP34 Antibody detects endogenous levels of total USP34 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | USP34 |
| Accession No. | Q70CQ2 |
| Alternate Names | Deubiquitinating enzyme 34; FLJ43910; KIAA0570; KIAA0729; MGC104459; Ubiquitin carboxyl terminal hydrolase 34; Ubiquitin carboxyl-terminal hydrolase 34; Ubiquitin specific processing protease 34; Ubiquitin specific protease 34; Ubiquitin thioesterase 34; Ubiquitin thiolesterase 34; Ubiquitin-specific-processing protease 34; UBP34_HUMAN; USP 34; Usp34; |
| Description | Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 404 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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