ITC0039
ITC0039
- Catalog: ITC0039
- Gene/Protein: CTSH
- Product Description: Immunotag™ Cathepsin H Polyclonal Antibody
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CathEPSin H |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Cathepsin H . at AA range: 220-300 |
| Specificity | Cathepsin H Polyclonal Antibody detects endogenous levels of Cathepsin H protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CTSH |
| Accession No. | P09668 P49935 |
| Alternate Names | CTSH; CPSB; Pro-cathepsin H |
| Description | cathepsin H(CTSH) Homo sapiens The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016], |
| Cell Pathway/ Category | Lysosome, |
| Protein Expression | Cartilage,Eye,Kidney,Liver,Lung,Salivary gland, |
| Subcellular Localization | extracellular space,lysosome,cytosol,extracellular exosome,alveolar lamellar body,multivesicular body lumen, |
| Protein Function | catalytic activity:Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-|-Xaa bonds) as well as an endopeptidase.,function:Important for the overall degradation of proteins in lysosomes.,similarity:Belongs to the peptidase C1 family.,subunit:Composed of a mini chain and a large chain. The large chain may be split into heavy and light chain. All chains are held together by disulfide bonds., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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