ITC0052
ITC0052
- Catalog: ITC0052
- Gene/Protein: EFNA2
- Product Description: Immunotag™ Cleaved-Ephrin-A2 (N188) Polyclonal Antibody
460.0000
Price in reward points: 460
| Antibody Specification | |
| Datasheet | 
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| Target Protein | EPHrin-A2 (N188) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human EFNA2. AA range:139-188 |
| Specificity | Cleaved-Ephrin-A2 (N188) Polyclonal Antibody detects endogenous levels of fragment of activated Ephrin-A2 protein resulting from cleavage adjacent to N188. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | EFNA2 |
| Accession No. | O43921 P52801 |
| Alternate Names | EFNA2; EPLG6; LERK6; Ephrin-A2; EPH-related receptor tyrosine kinase ligand 6; LERK-6; HEK7 ligand; HEK7-L |
| Description | ephrin A2(EFNA2) Homo sapiens This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Axon guidance, |
| Protein Expression | Brain, |
| Subcellular Localization | extracellular region,plasma membrane,anchored component of membrane,neuromuscular junction,perikaryon, |
| Protein Function | similarity:Belongs to the ephrin family.,subunit:Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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