Datasheet |
|
Target Protein |
EF-1 α1/2 (Lys41) |
Clonality |
Polyclonal |
Storage/Stability |
-20°C/1 year |
Application |
WB,ELISA |
Recommended Dilution |
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration |
1 mg/ml |
Reactive Species |
Human,Mouse,Rat |
Host Species |
Rabbit |
Immunogen |
Synthesized acetyl-peptide derived from the human EF-1 α1/2 around the acetylation site of K41. |
Specificity |
Acetyl-EF-1 α1/2 (K41) Polyclonal Antibody detects endogenous levels of EF-1 α1/2 protein only when acetylated at K41. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name |
EEF1A1/EEF1A2/EEF1A1P5 |
Accession No. |
P68104 P10126 P62630 |
Alternate Names |
EEF1A1; EEF1A; EF1A; LENG7; Elongation factor 1-alpha 1; EF-1-alpha-1; Elongation factor Tu; EF-Tu; Eukaryotic elongation factor 1 A-1; eEF1A-1; Leukocyte receptor cluster member 7; EEF1A2; EEF1AL; STN; Elongation factor 1-alpha 2; EF-1-alpha-2;Eukaryotic elongation factor 1 A-2; eEF1A-2; Statin-S1; EEF1A1P5; EEF1AL3; Putative elongation factor 1-alpha-like 3; EF-1-alpha-like 3; Eukaryotic elongation factor 1 A-like 3; eEF1A-like 3; Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5 |
Description |
eukaryotic translation elongation factor 1 alpha 1(EEF1A1) Homo sapiens This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008], |
Protein Expression |
Adipose tissue,Adrenal gland,B-cell,B-cell lymphoma |
Subcellular Localization |
extracellular space,nucleus,nucleolus,cytoplasm,cytosol,eukaryotic translation elongation factor 1 complex,membrane,cortical actin cytoskeleton,ruffle membrane,extracellular exosome,cytoplasmic side of lysos |
Protein Function |
caution:Could be the product of a pseudogene.,function:This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.,similarity:Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.,subunit:Found in a nuclear export complex with XPO5, EEF1A1, Ran and aminoacylated tRNA. Interacts with XPO5. May interact with ERGIC2.,tissue specificity:Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle., |
Usage |
For Research Use Only! Not for diagnostic or therapeutic procedures. |