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ITM0022

  • Gene/Protein: ALDH1A1
  • Product Description: Immunotag™ ALDH1A1 Monoclonal Antibody
  • 368.0000
    Price in reward points: 368

    Available Options

ITM0022

Immunotag™ ALDH1A1 Monoclonal Antibody
Antibody Specification
Datasheet
Target Protein ALDH1A1
Clonality Monoclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Mouse
Immunogen Purified recombinant fragment of human ALDH1A1 expressed in E. Coli.
Specificity ALDH1A1 Monoclonal Antibody detects endogenous levels of ALDH1A1 protein.
Purification Affinity purification
Form Ascitic fluid containing 0.03% sodium azide.
Gene Name ALDH1A1
Accession No. P00352 P24549
Alternate Names ALDH1A1; ALDC; ALDH1; PUMB1; Retinal dehydrogenase 1; RALDH 1; RalDH1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase; cytosolic
Description aldehyde dehydrogenase 1 family member A1(ALDH1A1) Homo sapiens The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011],
Cell Pathway/ Category Retinol metabolism,
Protein Expression Brain,Colon,Erythrocyte,Lens,Liver,
Subcellular Localization cytoplasm,cytosol,extracellular exosome,
Protein Function catalytic activity:Retinal + NAD(+) + H(2)O = retinoate + NADH.,function:Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid.,pathway:Cofactor metabolism; retinol metabolism.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homotetramer.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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