ITM0022
ITM0022
- Catalog: ITM0022
- Gene/Protein: ALDH1A1
- Product Description: Immunotag™ ALDH1A1 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ALDH1A1 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human ALDH1A1 expressed in E. Coli. |
| Specificity | ALDH1A1 Monoclonal Antibody detects endogenous levels of ALDH1A1 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | ALDH1A1 |
| Accession No. | P00352 P24549 |
| Alternate Names | ALDH1A1; ALDC; ALDH1; PUMB1; Retinal dehydrogenase 1; RALDH 1; RalDH1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase; cytosolic |
| Description | aldehyde dehydrogenase 1 family member A1(ALDH1A1) Homo sapiens The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011], |
| Cell Pathway/ Category | Retinol metabolism, |
| Protein Expression | Brain,Colon,Erythrocyte,Lens,Liver, |
| Subcellular Localization | cytoplasm,cytosol,extracellular exosome, |
| Protein Function | catalytic activity:Retinal + NAD(+) + H(2)O = retinoate + NADH.,function:Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid.,pathway:Cofactor metabolism; retinol metabolism.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homotetramer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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