ITM0041
ITM0041
- Catalog: ITM0041
- Gene/Protein: APOO
- Product Description: Immunotag™ ApoO Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ApoO |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of ApoO expressed in E. Coli. |
| Specificity | ApoO Monoclonal Antibody detects endogenous levels of ApoO protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | APOO |
| Accession No. | Q9BUR5 Q9DCZ4 |
| Alternate Names | APOO; FAM121B; My025; Apolipoprotein O; Protein FAM121B |
| Description | apolipoprotein O(APOO) Homo sapiens This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16.[provided by RefSeq, Sep 2009], |
| Protein Expression | Fetal brain,Lung,Skin,Urinary bladder, |
| Subcellular Localization | Golgi membrane,extracellular region,extracellular space,mitochondrion,endoplasmic reticulum membrane,integral component of mitochondrial inner membrane,very-low-density lipoprotein particle,low-density lipoprotein particle,high-density lipoprotein particle,M |
| Protein Function | function:Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.,PTM:O-glycosylation; glycosaminoglycan of chondroitin-sulfate type.,similarity:Belongs to the apolipoprotein O family.,tissue specificity:Expressed in all tissues examined. Up-regulated in diabetic heart., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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