ITM0113
ITM0113
- Catalog: ITM0113
- Gene/Protein: FCER2
- Product Description: Immunotag™ CD23 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD23 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | FCM,ELISA |
| Recommended Dilution | Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human CD23 expressed in E. Coli. |
| Specificity | CD23 Monoclonal Antibody detects endogenous levels of CD23 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | FCER2 |
| Accession No. | P06734 P20693 |
| Alternate Names | FCER2; CD23A; CLEC4J; FCE2; IGEBF; Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; CD antigen CD23 |
| Description | Fc fragment of IgE receptor II(FCER2) Homo sapiens The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011], |
| Cell Pathway/ Category | Hematopoietic cell lineage, |
| Protein Expression | B-cell,Blood, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,external side of plasma membrane,integral component of membrane,extracellular exosome, |
| Protein Function | function:This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).,miscellaneous:There are two kinds of Fc receptors for IgE, which differ in both structure and function: high affinity receptors on basophils and mast cells and low affinity receptors on lymphocytes and monocytes.,online information:CD23,PTM:N- and O-glycosylated.,similarity:Contains 1 C-type lectin domain.,subcellular location:Also exists as a soluble excreted form., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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