ITM0130
ITM0130
- Catalog: ITM0130
- Gene/Protein: CEACAM5
- Product Description: Immunotag™ CD66e Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD66e |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human CD66e expressed in E. Coli. |
| Specificity | CD66e Monoclonal Antibody detects endogenous levels of CD66e protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | CEACAM5 |
| Accession No. | P06731 Q3UKK2 |
| Alternate Names | CEACAM5; CEA; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD antigen CD66e |
| Description | carcinoembryonic antigen related cell adhesion molecule 5(CEACAM5) Homo sapiens This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015], |
| Protein Expression | Colon,Colon carcinoma,Liver,Saliva, |
| Subcellular Localization | integral component of plasma membrane,basolateral plasma membrane,anchored component of membrane,extracellular exosome,integral component of external side of plasma membrane, |
| Protein Function | function:Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.,PTM:Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 7 Ig-like (immunoglobulin-like) domains.,subunit:Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.,tissue specificity:Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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