ITM0150
ITM0150
- Catalog: ITM0150
- Gene/Protein: CER1
- Product Description: Immunotag™ Cerberus Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Cerberus |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human Cerberus expressed in E. Coli. |
| Specificity | Cerberus Monoclonal Antibody detects endogenous levels of Cerberus protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | CER1 |
| Accession No. | O95813 O55233 |
| Alternate Names | CER1; DAND4; Cerberus; Cerberus-related protein; DAN domain family member 4 |
| Description | cerberus 1, DAN family BMP antagonist(CER1) Homo sapiens This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | WNT,WNT-T CELL |
| Protein Expression | Blood,PCR rescued clones, |
| Subcellular Localization | extracellular region,extracellular space, |
| Protein Function | function:Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.,PTM:N-glycosylated.,sequence caution:Translated as Ser.,similarity:Belongs to the DAN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,subunit:Forms monomers and predominantly dimers., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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