ITM0165
ITM0165
- Catalog: ITM0165
- Gene/Protein: TDGF1
- Product Description: Immunotag™ Cripto Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Cripto |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human Cripto expressed in E. Coli. |
| Specificity | Cripto Monoclonal Antibody detects endogenous levels of Cripto protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | TDGF1 |
| Accession No. | P13385 P51865 |
| Alternate Names | TDGF1; CRIPTO; Teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1 |
| Description | teratocarcinoma-derived growth factor 1(TDGF1) Homo sapiens This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010], |
| Protein Expression | Brain,Kidney,Lung fibroblast, |
| Subcellular Localization | extracellular space,plasma membrane,cell surface,integral component of membrane,apical plasma membrane,extrinsic component of plasma membrane,anchored component of membrane,membrane raft, |
| Protein Function | function:Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.,similarity:Contains 1 EGF-like domain.,tissue specificity:Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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