ITM0178
ITM0178
- Catalog: ITM0178
- Gene/Protein: YES1
- Product Description: Immunotag™ c-Yes Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | c-Yes |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of c-Yes (aa10-193) expressed in E. Coli. |
| Specificity | c-Yes Monoclonal Antibody detects endogenous levels of c-Yes protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | YES1 |
| Accession No. | P07947 Q04736 |
| Alternate Names | YES1; YES; Tyrosine-protein kinase Yes; Proto-oncogene c-Yes; p61-Yes |
| Description | YES proto-oncogene 1, Src family tyrosine kinase(YES1) Homo sapiens This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Adherens_Junction,Adherens_Junction, |
| Protein Expression | Brain,Epithelium,Platelet,T-cell, |
| Subcellular Localization | cytoplasm,Golgi apparatus,microtubule organizing center,cytosol,actin filament,plasma membrane,focal adhesion,extrinsic component of cytoplasmic side of plasma membrane,extracellular exosome, |
| Protein Function | catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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