ITM0198
ITM0198
- Catalog: ITM0198
- Gene/Protein: DKK1
- Product Description: Immunotag™ Dkk-1 Monoclonal Antibody
504.0000
Price in reward points: 504
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Antibody Specification | |
Datasheet | |
Target Protein | DKK-1 |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Mouse |
Immunogen | Purified recombinant fragment of Dkk-1 expressed in E. Coli. |
Specificity | Dkk-1 Monoclonal Antibody detects endogenous levels of Dkk-1 protein. |
Purification | Affinity purification |
Form | Ascitic fluid containing 0.03% sodium azide. |
Gene Name | DKK1 |
Accession No. | O94907 O54908 |
Alternate Names | DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK |
Description | dickkopf WNT signaling pathway inhibitor 1(DKK1) Homo sapiens This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | WNT,WNT-T CELL |
Protein Expression | Brain,Fetal kidney,Leiomyosarcoma, |
Subcellular Localization | extracellular region,extracellular space,plasma membrane,early endosome membrane, |
Protein Function | function:Inhibitor of Wnt signaling pathway.,similarity:Belongs to the dickkopf family.,tissue specificity:Placenta., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |