ITM0199
ITM0199
- Catalog: ITM0199
- Gene/Protein: DKK3
- Product Description: Immunotag™ Dkk-3 Monoclonal Antibody
504.0000
Price in reward points: 504
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Antibody Specification | |
Datasheet | |
Target Protein | DKK-3 |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | WB,FCM,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Monkey |
Host Species | Mouse |
Immunogen | Purified recombinant fragment of human Dkk-3 expressed in E. Coli. |
Specificity | Dkk-3 Monoclonal Antibody detects endogenous levels of Dkk-3 protein. |
Purification | Affinity purification |
Form | Ascitic fluid containing 0.03% sodium azide. |
Gene Name | DKK3 |
Accession No. | Q9UBP4 Q9QUN9 |
Alternate Names | DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3 |
Description | dickkopf WNT signaling pathway inhibitor 3(DKK3) Homo sapiens This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008], |
Protein Expression | Fetal brain,Kidney,Liver, |
Subcellular Localization | extracellular region,extracellular space, |
Protein Function | function:Inhibitor of Wnt signaling pathway .,PTM:N-glycosylated.,similarity:Belongs to the dickkopf family.,tissue specificity:Highest expression in heart, brain, and spinal cord., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |