ITM0200
ITM0200
- Catalog: ITM0200
- Gene/Protein: DLK1
- Product Description: Immunotag™ DLK1 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DLK1 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,FCM,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human DLK1 expressed in E. Coli. |
| Specificity | DLK1 Monoclonal Antibody detects endogenous levels of DLK1 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | DLK1 |
| Accession No. | P80370 Q09163 |
| Alternate Names | DLK1; DLK; Protein delta homolog 1; DLK-1; pG2 |
| Description | delta like non-canonical Notch ligand 1(DLK1) Homo sapiens This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015], |
| Cell Pathway/ Category | Cell Growth |
| Protein Expression | Adrenal gland,Amniotic fluid,Brain,Placenta, |
| Subcellular Localization | extracellular space,integral component of membrane, |
| Protein Function | Additional isoforms seem to exist,function:May have a role in neuroendocrine differentiation.,PTM:N- and O-glycosylated.,similarity:Contains 6 EGF-like domains.,subunit:Monomer.,tissue specificity:Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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