ITM0212
ITM0212
- Catalog: ITM0212
- Gene/Protein: EGR1
- Product Description: Immunotag™ Egr-1 Monoclonal Antibody
504.0000
Price in reward points: 504
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Antibody Specification | |
Datasheet | |
Target Protein | EGR1 |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Mouse |
Immunogen | Purified recombinant fragment of human Egr-1 (aa282-433) expressed in E. Coli. |
Specificity | Egr-1 Monoclonal Antibody detects endogenous levels of Egr-1 protein. |
Purification | Affinity purification |
Form | Ascitic fluid containing 0.03% sodium azide. |
Gene Name | EGR1 |
Accession No. | P18146 P08046 |
Alternate Names | EGR1; KROX24; ZNF225; Early growth response protein 1; EGR-1; AT225; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24 |
Description | early growth response 1(EGR1) Homo sapiens The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014], |
Cell Pathway/ Category | Prion diseases, |
Protein Expression | Foreskin,PNS, |
Subcellular Localization | nucleus,nucleoplasm,cytoplasm, |
Protein Function | function:Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.,induction:By growth factors.,similarity:Belongs to the EGR C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |