ITM0293
ITM0293
- Catalog: ITM0293
- Gene/Protein: GABPA
- Product Description: Immunotag™ GABP-α Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GABP-α |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human GABP-α (aa120-190) expressed in E. Coli. |
| Specificity | GABP-α Monoclonal Antibody detects endogenous levels of GABP-α protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | GABPA |
| Accession No. | Q06546 Q00422 |
| Alternate Names | GABPA; E4TF1A; GA-binding protein alpha chain; GABP subunit alpha; Nuclear respiratory factor 2 subunit alpha; Transcription factor E4TF1-60 |
| Description | GA binding protein transcription factor alpha subunit(GABPA) Homo sapiens This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010], |
| Protein Expression | Brain,Hepatoma, |
| Subcellular Localization | nuclear chromatin,nucleus,nucleoplasm, |
| Protein Function | function:Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,similarity:Contains 1 PNT (pointed) domain.,subunit:Heterotetramer of two alpha and two beta subunits., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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