ITM0382
ITM0382
- Catalog: ITM0382
- Gene/Protein: ISL1
- Product Description: Immunotag™ Islet-1 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Islet-1 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human Islet-1 expressed in E. Coli. |
| Specificity | Islet-1 Monoclonal Antibody detects endogenous levels of Islet-1 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | ISL1 |
| Accession No. | P61371 P61372 |
| Alternate Names | ISL1; Insulin gene enhancer protein ISL-1; Islet-1 |
| Description | ISL LIM homeobox 1(ISL1) Homo sapiens This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008], |
| Protein Expression | Pancreatic islet,Platelet,Testis, |
| Subcellular Localization | nucleus,nucleoplasm,cytoplasm, |
| Protein Function | function:Binds to one of the cis-acting domain of the insulin gene enhancer.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,tissue specificity:Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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