ITM0451
ITM0451
- Catalog: ITM0451
- Gene/Protein: MSI1
- Product Description: Immunotag™ Msi1 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Msi1 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,FCM,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human Msi1 expressed in E. Coli. |
| Specificity | Msi1 Monoclonal Antibody detects endogenous levels of Msi1 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | MSI1 |
| Accession No. | O43347 Q61474 |
| Alternate Names | MSI1; RNA-binding protein Musashi homolog 1; Musashi-1 |
| Description | musashi RNA binding protein 1(MSI1) Homo sapiens This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008], |
| Protein Expression | Fetal brain, |
| Subcellular Localization | nucleus,cytoplasm,polysome, |
| Protein Function | domain:The first RNA recognition motif binds more strongly to RNA compared to the second one.,function:RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.,similarity:Belongs to the Musashi family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,tissue specificity:Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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