ITM0554
ITM0554
- Catalog: ITM0554
- Gene/Protein: RBP4
- Product Description: Immunotag™ RBP4 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | RBP4 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,FCM,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human RBP4 expressed in E. Coli. |
| Specificity | RBP4 Monoclonal Antibody detects endogenous levels of RBP4 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | RBP4 |
| Accession No. | P02753 Q00724 |
| Alternate Names | RBP4; Retinol-binding protein 4; Plasma retinol-binding protein; PRBP; RBP |
| Description | retinol binding protein 4(RBP4) Homo sapiens This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008], |
| Protein Expression | Fetal liver,Liver, |
| Subcellular Localization | extracellular region,extracellular space,cytosol,protein complex,extracellular exosome, |
| Protein Function | disease:A deficiency of vitamin A blocks secretion of the binding protein post-translationally and results in defective delivery and supply of vitamin to the epidermal cells (a condition associated with a dermatosis).,disease:Defects in RBP4 are a cause of retinol-binding protein deficiency [MIM:180250]. This condition causes night vision problems. It produces a typical "fundus xerophthalmicus," featuring a progressed atrophy of the retinal pigment epithelium.,function:Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.,mass spectrometry: PubMed:12237133,mass spectrometry: PubMed:7666002,online information:Retina International's Scientific Newsletter,online information:Retinol-binding protein 4 entry,similarity:Belongs to the calycin superfamily. Lipocalin family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|