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ITM0589

ITM0589
  • Gene/Protein: SNAI1
  • Product Description: Immunotag™ SNAI 1 Monoclonal Antibody
368.0000
Price in reward points: 368

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Immunotag™ SNAI 1 Monoclonal Antibody
Antibody Specification
Datasheet
Target Protein SNAI 1
Clonality Monoclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Mouse
Immunogen Purified recombinant fragment of human SNAI 1 expressed in E. Coli.
Specificity SNAI 1 Monoclonal Antibody detects endogenous levels of SNAI 1 protein.
Purification Affinity purification
Form Ascitic fluid containing 0.03% sodium azide.
Gene Name SNAI1
Accession No. O95863 Q02085
Alternate Names SNAI1; SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna
Description snail family transcriptional repressor 1(SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Adherens_Junction,
Protein Expression Epithelium,Mammary gland,Testis,
Subcellular Localization nucleus,cytoplasm,
Protein Function function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.,similarity:Belongs to the snail C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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