ITM0617
ITM0617
- Catalog: ITM0617
- Gene/Protein: THAP11
- Product Description: Immunotag™ THAP11 Monoclonal Antibody
504.0000
Price in reward points: 504
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Antibody Specification | |
Datasheet | |
Target Protein | THAP11 |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,FCM,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Mouse |
Immunogen | Purified recombinant fragment of human THAP11 expressed in E. Coli. |
Specificity | THAP11 Monoclonal Antibody detects endogenous levels of THAP11 protein. |
Purification | Affinity purification |
Form | Ascitic fluid containing 0.03% sodium azide. |
Gene Name | THAP11 |
Accession No. | Q96EK4 Q9JJD0 |
Alternate Names | THAP11; HRIHFB2206; THAP domain-containing protein 11 |
Description | THAP domain containing 11(THAP11) Homo sapiens The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008], |
Protein Expression | Brain,Neuroblastoma,Uterus, |
Subcellular Localization | nucleoplasm,cytoplasm,intercellular bridge, |
Protein Function | function:Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.,polymorphism:The length of the poly-Gln region is variable in the population.,similarity:Belongs to the THAP11 family.,similarity:Contains 1 THAP-type zinc finger.,subcellular location:May be regulated by shuttling of the protein between the cytoplasm and nucleus.,subunit:Interacts (via coiled coil domain) with HCFC1., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |