ITM0650
ITM0650
- Catalog: ITM0650
- Gene/Protein: WNT10B
- Product Description: Immunotag™ Wnt-10b Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Wnt-10b |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human Wnt-10b expressed in E. Coli. |
| Specificity | Wnt-10b Monoclonal Antibody detects endogenous levels of Wnt-10b protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | WNT10B |
| Accession No. | O00744 P48614 |
| Alternate Names | WNT10B; WNT12; Protein Wnt-10b; Protein Wnt-12 |
| Description | Wnt family member 10B(WNT10B) Homo sapiens The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | WNT,WNT-T CELLHedgehog,Melanogenesis,Pathways in cancer,Basal cell carcinoma, |
| Protein Expression | Fetal brain,PCR rescued clones,Placenta, |
| Subcellular Localization | extracellular region,proteinaceous extracellular matrix,extracellular space, |
| Protein Function | developmental stage:Infant brain has higher levels of WNT10B than adult brain.,function:Ligand for members of the frizzled family of seven transmembrane receptors.,function:Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.,similarity:Belongs to the Wnt family.,tissue specificity:Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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