ITM1057
ITM1057
- Catalog: ITM1057
- Gene/Protein: LRRFIP1
- Product Description: Immunotag™ LRRFIP1 Monoclonal Antibody
504.0000
Price in reward points: 504
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Antibody Specification | |
Datasheet | |
Target Protein | LRRFIP1 |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | WB |
Recommended Dilution | Western Blot: 1/1000 - 1/2000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Mouse |
Immunogen | Purified recombinant human LRRFIP1 protein fragments expressed in E.coli. |
Specificity | LRRFIP1 Monoclonal Antibody detects endogenous levels of LRRFIP1 protein. |
Purification | Affinity purification |
Form | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol. |
Gene Name | LRRFIP1 |
Accession No. | Q32MZ4 Q3UZ39 |
Alternate Names | LRRFIP1; GCF2; TRIP; Leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; GC-binding factor 2; TAR RNA-interacting protein |
Description | developmental stage:Widely expressed in fetal tissues.,function:Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the LRRFIP family.,subunit:Interacts with FLII.,tissue specificity:Ubiquitously expressed., |
Protein Expression | Cervix carcinoma,Colon,Epithelium,Heart,Kidney,Melanoma,Ovarian car |
Subcellular Localization | nucleus,cytoplasm,cytosol,cytoskeleton,plasma membrane,cell-cell adherens junction, |
Protein Function | developmental stage:Widely expressed in fetal tissues.,function:Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the LRRFIP family.,subunit:Interacts with FLII.,tissue specificity:Ubiquitously expressed., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |