ITM1452
ITM1452
- Catalog: ITM1452
- Gene/Protein: ngal
- Product Description: Immunotag™ NGAL mouse mAb
405.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NGAL |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | ELISA |
Recommended Dilution | ELISA 1:10000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Mouse |
Immunogen | Recombinant protein of human NGAL. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ngal |
Accession No. | P80188 P11672 |
Alternate Names | 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; HNL; Lcn2; Lipocalin 2; Lipocalin-2; Migration stimulating factor inhibitor; MSFI; Neutrophil gelatinase-associated lipocalin; NGAL; NGAL_HUMAN; Oncogene 24p3; p25; Siderocalin. |
Description | lipocalin 2(LCN2) Homo sapiens This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015], |
Protein Expression | Bile,Bone marrow,Liver,Neutrophil,Pancreas,Plasma,Saliva, |
Subcellular Localization | extracellular region,extracellular space,cell,cytosol,extracellular exosome, |
Protein Function | function:Transport of small lipophilic substances .,similarity:Belongs to the calycin superfamily. Lipocalin family.,subunit:Forms a covalently linked, disulfide-bridged heterodimer with the 92 kDa type V collagenase (MMP-9).,tissue specificity:Expressed in bone marrow and in tissues that are prone to exposure to microorganism. High expression is found in bone marrow as well as in uterus, prostate, salivary gland, stomach, appendix, colon, trachea and lungs. Not found in the small intestine or peripheral blood leukocytes., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |