ITM1459
ITM1459
- Catalog: ITM1459
- Gene/Protein: wnt3a
- Product Description: Immunotag™ Wnt3a mouse mAb
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Wnt-3a |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB |
| Recommended Dilution | wb dilution 1:1000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant Wnt3a protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of Wnt3a and Wnt3. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | wnt3a |
| Accession No. | P56704 P27467 |
| Alternate Names | MGC119418 ;MGC119419 ;MGC119420 ;Protein Wnt 3a Precursor ;Protein Wnt-3a ;Wingless type MMTV integration site family member 3A ;Wnt 3a ;wnt3a ;WNT3A protein ;WNT3A_HUMAN. |
| Description | Wnt family member 3A(WNT3A) Homo sapiens The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | WNT,WNT-T CELLHedgehog,Melanogenesis,Pathways in cancer,Basal cell carcinoma, |
| Protein Expression | Mammary gland,PCR rescued clones, |
| Subcellular Localization | extracellular region,proteinaceous extracellular matrix,extracellular space,endoplasmic reticulum lumen,Golgi lumen,plasma membrane,cell surface,endocytic vesicle membrane,early endosome membrane,extracellular exosome,presynapse, |
| Protein Function | function:Ligand for members of the frizzled family of seven transmembrane receptors.,function:Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.,similarity:Belongs to the Wnt family.,subunit:Interacts with PORCN.,tissue specificity:Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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