ITM1470
ITM1470
- Catalog: ITM1470
- Gene/Protein: got2
- Product Description: Immunotag™ GOT2 mouse mAb
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GOT2 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Mouse |
| Immunogen | Recombinant protein corresponding to fragment (aa/225-430) GOT2 . |
| Specificity | This antibody detects endogenous levels of GOT2. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | got2 |
| Accession No. | P00505 P05202 |
| Alternate Names | AATM_HUMAN ；AL022787 ；Aspartate aminotransferase ；Aspartate aminotransferase 2 ；Aspartate aminotransferase, mitochondrial ；ASPATA ；EC 2.6.1.1 ；FABP 1 ；FABP pm ；FABP-1 ；FABPpm ；Fatty acid binding protein ；Fatty acid-binding protein ；FLJ40994 ；Glutamate oxaloacetate transaminase 2 ；Glutamate oxaloacetate transaminase 2, mitochondrial ；Glutamate oxaloacetate transaminase, mitochondrial ；Glutamic oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) ；Got 2 ；GOT2 ；KAT4 ；KATIV ；Kynurenine aminotransferase IV ；mAspAT ；MGC102129 ；MGC115763 ；mitAAT ；mitochondrial ；Mitochondrial aspartate aminotransferase ；OTTMUSP00000017748 ；Plasma membrane fatty acid binding protein ；Plasma membrane-associated fatty acid-binding protein ；Transaminase A. |
| Description | glutamic-oxaloacetic transaminase 2(GOT2) Homo sapiens Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013], |
| Cell Pathway/ Category | Alanine, aspartate and glutamate metabolism,Cysteine and methionine metabolism,Arginine and proline metabolism,Tyrosine metabolism,Phenylalanine metabolism,Phenylalanine, tyrosine and tryptophan biosynthesis, |
| Protein Expression | Epithelium,Gastric mucosa,Muscle, |
| Subcellular Localization | mitochondrion,mitochondrial inner membrane,mitochondrial matrix,plasma membrane,cell surface,perikaryon,myelin sheath,protein complex,extracellular exosome, |
| Protein Function | catalytic activity:L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.,cofactor:Pyridoxal phosphate.,function:Facilitates cellular uptake of long-chain free fatty acids.,miscellaneous:In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.,similarity:Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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