ITM1504
ITM1504
- Catalog: ITM1504
- Gene/Protein: rbp4
- Product Description: Immunotag™ RBP4 mouse mAb
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RBP4 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | ELISA |
| Recommended Dilution | ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant human RBP4 protein fragments expressed in E.coli. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | rbp4 |
| Accession No. | P02753 Q00724 |
| Alternate Names | OTTHUMP00000020114;OTTHUMP00000020115;OTTHUMP00000020116;Plasma retinol binding protein 4;Plasma retinol-binding protein;Plasma retinol-binding protein(1-176);PRBP;PRO2222;RBP;RBP4;RDCCAS;RET4_HUMAN;Retinol binding protein 4;Retinol binding protein 4 interstitial;Retinol binding protein 4 plasma. |
| Description | retinol binding protein 4(RBP4) Homo sapiens This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008], |
| Protein Expression | Fetal liver,Liver, |
| Subcellular Localization | extracellular region,extracellular space,cytosol,protein complex,extracellular exosome, |
| Protein Function | disease:A deficiency of vitamin A blocks secretion of the binding protein post-translationally and results in defective delivery and supply of vitamin to the epidermal cells (a condition associated with a dermatosis).,disease:Defects in RBP4 are a cause of retinol-binding protein deficiency [MIM:180250]. This condition causes night vision problems. It produces a typical "fundus xerophthalmicus," featuring a progressed atrophy of the retinal pigment epithelium.,function:Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.,mass spectrometry: PubMed:12237133,mass spectrometry: PubMed:7666002,online information:Retina International's Scientific Newsletter,online information:Retinol-binding protein 4 entry,similarity:Belongs to the calycin superfamily. Lipocalin family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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