ITM3063
ITM3063
- Catalog: ITM3063
- Gene/Protein: KIF7
- Product Description: Immunotag™ Kif 7 Monoclonal Antibody(3F8)
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Kif 7 (3F8) |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-P,IF |
| Recommended Dilution | IHC 1:200 IF 1:50-200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Mouse |
| Immunogen | Synthetic Peptide of Kif 7 |
| Specificity | The antibody detects endogenous Kif 7 proteins. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | KIF7 |
| Accession No. | Q2M1P5 B7ZNG0 |
| Alternate Names | Kinesin-like protein KIF7 |
| Description | kinesin family member 7(KIF7) Homo sapiens This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011], |
| Protein Expression | Heart,Lung,Ovary, |
| Subcellular Localization | kinesin complex,cilium,ciliary tip, |
| Protein Function | similarity:Belongs to the kinesin-like protein family. KIF27 subfamily.,similarity:Contains 1 kinesin-motor domain.,tissue specificity:Embryonic stem cells, melanotic melanoma and Jurkat T-cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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