ITM3069
ITM3069
- Catalog: ITM3069
- Gene/Protein: CD2
- Product Description: Immunotag™ CD2 Monoclonal Antibody(3F3)
405.0000
Price in reward points: 405
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Antibody Specification | |
Datasheet | |
Target Protein | CD2 (3F3) |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p |
Recommended Dilution | IHC: 1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Mouse |
Immunogen | Synthetic Peptide of CD2 |
Specificity | The antibody detects endogenous CD2 proteins. |
Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen |
Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
Gene Name | CD2 |
Accession No. | P06729 P08920 P08921 |
Alternate Names | CD2; SRBC; T-cell surface antigen CD2; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD2 |
Description | CD2 molecule(CD2) Homo sapiens The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016], |
Cell Pathway/ Category | Cell adhesion molecules (CAMs),Hematopoietic cell lineage, |
Protein Expression | Pancreas,Spleen,Thymus, |
Subcellular Localization | extracellular region,plasma membrane,integral component of plasma membrane,cell-cell junction,external side of plasma membrane,cytoplasmic side of plasma membrane,cell surface,integral component of membrane,anchored component of plasma membrane, |
Protein Function | function:CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.,online information:CD2 entry,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD2AP (By similarity). Interacts with PSTPIP1., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |