ITM3089
ITM3089
- Catalog: ITM3089
- Gene/Protein: POU2F1
- Product Description: Immunotag™ Oct1 Monoclonal Antibody(7G1)
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Oct1 (7G1) |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF, |
| Recommended Dilution | WB: 1:500-2000 IF 1:200 IHC 1:50-300 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Synthetic Peptide of 42644 |
| Specificity | The antibody detects endogenous Oct1 protein. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | POU2F1 |
| Accession No. | P14859/P09086 P31503 |
| Description | POU class 2 homeobox 1(POU2F1) Homo sapiens The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010], |
| Protein Expression | B-cell lymphoma,Epithelium,Lung,Lymph,Skin,Teratocarcinoma, |
| Subcellular Localization | nucleus,nucleoplasm,endoplasmic reticulum,intracellular membrane-bounded organelle, |
| Protein Function | function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.,PTM:Phosphorylated by PRKDC.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR, PGR and HCFC1.,tissue specificity:Ubiquitous. Isoform 2 is lymphocyte-specific., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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