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ITM3306

ITM3306
ITM3306
  • Gene/Protein: Kine
  • Product Description: Immunotag™ Acetyl Kine Polyclonal Antibody
  • 336.0000
    Price in reward points: 336

    Available Options

ITM3306

Immunotag™ Acetyl Kine Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein Kine
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB
Recommended Dilution WB: 1:500-1:2000, EIA: 1:20000
Concentration 1 mg/ml
Reactive Species All
Host Species Rabbit
Immunogen Recombinant Protein of Acetyl Kine
Specificity The antibody detects endogenous Lysine Acetylated protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen
Form Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Gene Name Kine
Description Acetylation of lysine, like phosphorylation of serine, threonine or tyrosine, is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) .Signaling resulting in acetylation/deacetylation of histones, transcription factors, and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity, cell growth, differentiation, and apoptosis.Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport.The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases, and HDACs have become promising targets for anti-cancer drugs currently in development.
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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