ITM3344
ITM3344
- Catalog: ITM3344
- Gene/Protein: ATP1B1
- Product Description: Immunotag™ beta 1 Sodium Potassium ATPase Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | b1 Sod. Pot. ATPase |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB |
| Recommended Dilution | WB: 1:1000-2000 |
| Concentration | 1 mg/ml |
| Reactive Species | Mouse,Rat,(H) |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of beta 1 Sodium Potassium ATPase |
| Specificity | The antibody detects endogenous beta 1 Sodium Potassium ATPase protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | ATP1B1 |
| Accession No. | P05026 P14094 P07340 |
| Alternate Names | Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1) |
| Description | ATPase Na+/K+ transporting subunit beta 1(ATP1B1) Homo sapiens The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript |
| Cell Pathway/ Category | Cardiac muscle contraction,Aldosterone-regulated sodium reabsorption, |
| Protein Expression | Kidney,Liver,Retinal pigment epithelium,Sperm,Thalamus,Uter |
| Subcellular Localization | intracellular,plasma membrane,sodium:potassium-exchanging ATPase complex,caveola,intercalated disc,membrane,basolateral plasma membrane,apical plasma membrane,sarcolemma,myelin sheath,extracellular exosome, |
| Protein Function | function:This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.,function:This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.,similarity:Belongs to the X(+)/potassium ATPases subunit beta family.,subunit:Composed of three subunits: alpha (catalytic), beta and gamma.,subunit:Composed of three subunits: alpha (catalytic), beta and gamma. Interacts with NKAIN1, NKAIN2 and NKAIN4.,tissue specificity:Found in most tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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