ITM3384
ITM3384
- Catalog: ITM3384
- Gene/Protein: BEST2
- Product Description: Immunotag™ BEST2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | BEST2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p |
| Recommended Dilution | WB: 1:500-1000 IHC: 1:200-500 |
| Concentration | 1 mg/ml |
| Reactive Species | Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of BEST2 |
| Specificity | The antibody detects endogenous BEST2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | BEST2 |
| Accession No. | Q8NFU1 Q8BGM5 |
| Alternate Names | Bestrophin-2; Vitelliform macular dystrophy 2-like protein 1 |
| Description | bestrophin 2(BEST2) Homo sapiens This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008], |
| Protein Expression | Colon, |
| Subcellular Localization | integral component of plasma membrane,cilium,chloride channel complex, |
| Protein Function | function:Forms calcium-sensitive chloride channels. May conduct other physiologically significant anions such as bicarbonate.,similarity:Belongs to the bestrophin family.,tissue specificity:Mainly confined to the retinal pigment epithelium and colon., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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