ITM3558
ITM3558
- Catalog: ITM3558
- Gene/Protein: GLP1R
- Product Description: Immunotag™ GLP1R Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GLP1R |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p |
| Recommended Dilution | WB 1:500-1000, IHC 1:50-100 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of GLP1R |
| Specificity | GLP1R protein(A233) detects endogenous levels of GLP1R |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GLP1R |
| Accession No. | P43220 O35659 P32301 |
| Alternate Names | GLP1R; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R |
| Description | glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Gastric carcinoma,Insulinoma,Pancreas,Pancreatic islet,Placenta, |
| Subcellular Localization | intracellular,plasma membrane,integral component of membrane, |
| Protein Function | function:This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,online information:Glucagon-like peptide 1 entry,similarity:Belongs to the G-protein coupled receptor 2 family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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