ITM3716
ITM3716
- Catalog: ITM3716
- Gene/Protein: DNAJB1 DNAJ1 HDJ1 HSPF1
- Product Description: Immunotag™ HSP40 Rabbit Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | HSP40 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p |
| Recommended Dilution | WB 1:500-2000,IHC-p 1:50-300 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Recombinant Protein of HSP40 |
| Specificity | The antibody detects endogenous HSP40 protein |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DNAJB1 DNAJ1 HDJ1 HSPF1 |
| Accession No. | P25685 Q9QYJ3 |
| Alternate Names | DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1) |
| Description | DnaJ heat shock protein family (Hsp40) member B1(DNAJB1) Homo sapiens This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015], |
| Protein Expression | Brain,Heart,Lung,Placenta, |
| Subcellular Localization | nucleus,nucleoplasm,nucleolus,cytoplasm,cytosol,cell-cell adherens junction,extracellular exosome, |
| Protein Function | function:Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP.,induction:By heat shock.,similarity:Contains 1 J domain.,subcellular location:Translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock.,subunit:Interacts with DNAJC3., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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