ITM6014
ITM6014
- Catalog: ITM6014
- Gene/Protein: FCER2 CD23A CLEC4J FCE2 IGEBF
- Product Description: Immunotag™ CD23 (ABT-CD23) mouse mAb
490.0000
Price in reward points: 490
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD23 (1H1) |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p |
| Recommended Dilution | IHC-p 1:100-500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Synthesized peptide derived from human CD23 |
| Specificity | This antibody detects endogenous levels of human CD23 |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | FCER2 CD23A CLEC4J FCE2 IGEBF |
| Accession No. | P06734 |
| Alternate Names | Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleaved into: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form] |
| Description | Fc fragment of IgE receptor II(FCER2) Homo sapiens The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011], |
| Cell Pathway/ Category | Hematopoietic cell lineage, |
| Protein Expression | B-cell,Blood, |
| Subcellular Localization | Membranous |
| Protein Function | function:This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).,miscellaneous:There are two kinds of Fc receptors for IgE, which differ in both structure and function: high affinity receptors on basophils and mast cells and low affinity receptors on lymphocytes and monocytes.,online information:CD23,PTM:N- and O-glycosylated.,similarity:Contains 1 C-type lectin domain.,subcellular location:Also exists as a soluble excreted form., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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